A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology

BACKGROUND: Genetic variation in NOD2 and cigarette smoking are well-established risk factors for the development of Crohn's disease (CD). However, little is known about a potential interaction between these risk factors. We investigated gene-environment interactions between CD-associated NOD2...

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Detalhes bibliográficos
Main Authors: Helbig, Katherine L, Nothnagel, Michael, Hampe, Jochen, Balschun, Tobias, Nikolaus, Susanna, Schreiber, Stefan, Franke, Andre, Nöthlings, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314543/
https://ncbi.nlm.nih.gov/pubmed/22416979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-14
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