The NOD2-Smoking Interaction in Crohn's Disease is likely Specific to the 1007 fs Mutation and may be Explained by Age at Diagnosis: A Meta-Analysis and Case-Only Study

BACKGROUND: NOD2 and smoking are risk factors for Crohn's disease. We meta-analyzed NOD2-smoking interactions in Crohn's disease (Phase 1), then explored the effect of age at diagnosis on NOD2-smoking interactions (Phase 2). METHODS: Phase 1: MEDLINE and EMBASE were searched for studies (n...

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Vydáno v:EBioMedicine
Hlavní autoři: Kuenzig, M. Ellen, Yim, Jeff, Coward, Stephanie, Eksteen, Bertus, Seow, Cynthia H., Barnabe, Cheryl, Barkema, Herman W., Silverberg, Mark S., Lakatos, Peter L., Beck, Paul L., Fedorak, Richard, Dieleman, Levinus A., Madsen, Karen, Panaccione, Remo, Ghosh, Subrata, Kaplan, Gilaad G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514403/
https://ncbi.nlm.nih.gov/pubmed/28668336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.012
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