The NOD2-Smoking Interaction in Crohn's Disease is likely Specific to the 1007 fs Mutation and may be Explained by Age at Diagnosis: A Meta-Analysis and Case-Only Study

BACKGROUND: NOD2 and smoking are risk factors for Crohn's disease. We meta-analyzed NOD2-smoking interactions in Crohn's disease (Phase 1), then explored the effect of age at diagnosis on NOD2-smoking interactions (Phase 2). METHODS: Phase 1: MEDLINE and EMBASE were searched for studies (n...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Kuenzig, M. Ellen, Yim, Jeff, Coward, Stephanie, Eksteen, Bertus, Seow, Cynthia H., Barnabe, Cheryl, Barkema, Herman W., Silverberg, Mark S., Lakatos, Peter L., Beck, Paul L., Fedorak, Richard, Dieleman, Levinus A., Madsen, Karen, Panaccione, Remo, Ghosh, Subrata, Kaplan, Gilaad G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514403/
https://ncbi.nlm.nih.gov/pubmed/28668336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.012
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