The NOD2-Smoking Interaction in Crohn's Disease is likely Specific to the 1007 fs Mutation and may be Explained by Age at Diagnosis: A Meta-Analysis and Case-Only Study

BACKGROUND: NOD2 and smoking are risk factors for Crohn's disease. We meta-analyzed NOD2-smoking interactions in Crohn's disease (Phase 1), then explored the effect of age at diagnosis on NOD2-smoking interactions (Phase 2). METHODS: Phase 1: MEDLINE and EMBASE were searched for studies (n...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Kuenzig, M. Ellen, Yim, Jeff, Coward, Stephanie, Eksteen, Bertus, Seow, Cynthia H., Barnabe, Cheryl, Barkema, Herman W., Silverberg, Mark S., Lakatos, Peter L., Beck, Paul L., Fedorak, Richard, Dieleman, Levinus A., Madsen, Karen, Panaccione, Remo, Ghosh, Subrata, Kaplan, Gilaad G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514403/
https://ncbi.nlm.nih.gov/pubmed/28668336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.012
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