Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages

od Hedl, Matija, Abraham, Clara
Wydane 2011

Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages

od Hedl, Matija, Abraham, Clara
Wydane 2010

CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells

od Sarin, Ritu, Abraham, Clara
Wydane 2012

IRF5 Risk Polymorphisms Contribute to Inter-Individual Variance in Pattern-Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells

od Hedl, Matija, Abraham, Clara
Wydane 2012

Nod2-Induced Autocrine Interleukin-1 Alters Signaling by ERK and p38 to Differentially Regulate Secretion of Inflammatory Cytokines

od Hedl, Matija, Abraham, Clara
Wydane 2012

NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation

od Hedl, Matija, Abraham, Clara
Wydane 2013

NF-κB1 Inhibits NOD2-Induced Cytokine Secretion through ATF3-Dependent Mechanisms

od Zheng, Shasha, Abraham, Clara
Wydane 2013

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

od Abraham, Clara, Medzhitov, Ruslan
Wydane 2011

A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1

od Hedl, Matija, Abraham, Clara
Wydane 2014

Activation of Pattern Recognition Receptors Upregulates Metallothioneins, Thereby Increasing Intracellular Accumulation of Zinc, Autophagy, and Bacterial Clearance by Macrophages

od Lahiri, Amit, Abraham, Clara
Wydane 2014

A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalli...

od Hedl, Matija, Abraham, Clara
Wydane w Gut (2015)

IL23 Promotes Antimicrobial Pathways in Human Macrophages, Which Are Reduced With the IBD-Protective IL23R R381Q Variant

od Sun, Rui, Abraham, Clara
Wydane w Cell Mol Gastroenterol Hepatol (2020)

Inflammatory Bowel Disease

od Abraham, Clara, Cho, Judy H.
Wydane 2009

Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

od Sarin, Ritu, Wu, Xingxin, Abraham, Clara
Wydane 2011

The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling Through Innate Receptor-Initiated Pathways

od Hedl, Matija, Zheng, Shasha, Abraham, Clara
Wydane 2014

TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to pro-inflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages()

od Zheng, Shasha, Hedl, Matija, Abraham, Clara
Wydane w J Immunol (2015)

Twist1 and Twist2 contribute to cytokine downregulation following chronic NOD2 stimulation of human macrophages through the coordinated regulation of transcriptional repressors and...

od Zheng, Shasha, Hedl, Matija, Abraham, Clara
Wydane w J Immunol (2015)

MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation

od Lahiri, Amit, Hedl, Matija, Abraham, Clara
Wydane w Proc Natl Acad Sci U S A (2015)

IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 polarization By Regulating Proximal Signaling and Akt2 Activation

od Hedl, Matija, Yan, Jie, Abraham, Clara
Wydane w Cell Rep (2016)

An inflammatory bowel disease–risk variant in INAVA decreases pattern recognition receptor–induced outcomes

od Yan, Jie, Hedl, Matija, Abraham, Clara
Wydane w J Clin Invest (2017)