A carregar...
A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion
OBJECTIVE: IBD is characterised by dysregulated intestinal immune homeostasis and cytokine secretion. In the intestine, properly regulating pattern recognition receptor (PRR)-mediated signalling and cytokines is crucial given the ongoing host–microbial interactions. TPL2 (MAP3K8, COT) contributes to...
Na minha lista:
| Publicado no: | Gut |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106344/ https://ncbi.nlm.nih.gov/pubmed/26215868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308922 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|