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IRF5 Risk Polymorphisms Contribute to Inter-Individual Variance in Pattern-Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells
Monocyte-derived cells display highly variable cytokine secretion upon pattern-recognition receptor (PRR) stimulation across individuals; such variability likely affects inter-individual inflammatory/autoimmune disease susceptibility. To define mechanisms for this heterogeneity, we examined pattern...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409850/ https://ncbi.nlm.nih.gov/pubmed/22544929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103319 |
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