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IRF5 Risk Polymorphisms Contribute to Inter-Individual Variance in Pattern-Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells

Monocyte-derived cells display highly variable cytokine secretion upon pattern-recognition receptor (PRR) stimulation across individuals; such variability likely affects inter-individual inflammatory/autoimmune disease susceptibility. To define mechanisms for this heterogeneity, we examined pattern...

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Bibliografische gegevens
Hoofdauteurs: Hedl, Matija, Abraham, Clara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409850/
https://ncbi.nlm.nih.gov/pubmed/22544929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103319
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