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Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages

BACKGROUND AND OBJECTIVES: Nod2 polymorphisms increase the risk for developing Crohn’s disease, characterized by chronic intestinal inflammation. Bacterial peptidoglycan products chronically stimulate Nod2 in the intestine. Recent studies found that chronic Nod2 stimulation in human macrophages down...

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Detalhes bibliográficos
Main Authors: Hedl, Matija, Abraham, Clara
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145247/
https://ncbi.nlm.nih.gov/pubmed/20854823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.09.009
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