Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn Disease

There has been considerable recent success in the detection of gene-disease associations. We consider here the development of tools that facilitate the more detailed characterization of the effect of a genetic variant on disease. We replace the simplistic classification of individuals according to a...

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Autores principales: Chapman, Juliet M., Onnie, Clive M., Prescott, Natalie J., Fisher, Sheila A., Mansfield, John C., Mathew, Christopher G., Lewis, Cathryn M., Verzilli, Claudio J., Whittaker, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668013/
https://ncbi.nlm.nih.gov/pubmed/19185283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.12.015
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