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HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes
Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...
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Principais autores: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065693/ https://ncbi.nlm.nih.gov/pubmed/21300701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr061 |
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