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HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...

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Detalhes bibliográficos
Principais autores: Dilthey, Alexander T., Moutsianas, Loukas, Leslie, Stephen, McVean, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065693/
https://ncbi.nlm.nih.gov/pubmed/21300701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr061
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