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HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...

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書誌詳細
主要な著者: Dilthey, Alexander T., Moutsianas, Loukas, Leslie, Stephen, McVean, Gil
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065693/
https://ncbi.nlm.nih.gov/pubmed/21300701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr061
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