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Multi-Population Classical HLA Type Imputation

Statistical imputation of classical HLA alleles in case-control studies has become established as a valuable tool for identifying and fine-mapping signals of disease association in the MHC. Imputation into diverse populations has, however, remained challenging, mainly because of the additional haplo...

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Main Authors: Dilthey, Alexander, Leslie, Stephen, Moutsianas, Loukas, Shen, Judong, Cox, Charles, Nelson, Matthew R., McVean, Gil
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572961/
https://ncbi.nlm.nih.gov/pubmed/23459081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002877
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