HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...

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Bibliografiske detaljer
Main Authors: Dilthey, Alexander T., Moutsianas, Loukas, Leslie, Stephen, McVean, Gil
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065693/
https://ncbi.nlm.nih.gov/pubmed/21300701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr061
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