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HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...

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Hlavní autoři: Dilthey, Alexander T., Moutsianas, Loukas, Leslie, Stephen, McVean, Gil
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065693/
https://ncbi.nlm.nih.gov/pubmed/21300701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr061
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