Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

The combining of genome-wide association (GWA) data across populations represents a major challenge for massive global meta-analyses. Genotype imputation using densely genotyped reference samples facilitates the combination of data across different genotyping platforms. HapMap data is typically used...

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Detalles Bibliográficos
Autores principales: Surakka, Ida, Kristiansson, Kati, Anttila, Verneri, Inouye, Michael, Barnes, Chris, Moutsianas, Loukas, Salomaa, Veikko, Daly, Mark, Palotie, Aarno, Peltonen, Leena, Ripatti, Samuli
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945183/
https://ncbi.nlm.nih.gov/pubmed/20810666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.106534.110
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