Use of Genome-Wide Expression Data to Mine the “Gray Zone” of GWA Studies Leads to Novel Candidate Obesity Genes

To get beyond the “low-hanging fruits” so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to complex human phenotypes, such as obesity. Here we desc...

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Main Authors: Naukkarinen, Jussi, Surakka, Ida, Pietiläinen, Kirsi H., Rissanen, Aila, Salomaa, Veikko, Ripatti, Samuli, Yki-Järvinen, Hannele, van Duijn, Cornelia M., Wichmann, H.-Erich, Kaprio, Jaakko, Taskinen, Marja-Riitta, Peltonen, Leena
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880558/
https://ncbi.nlm.nih.gov/pubmed/20532202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000976
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