Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

অনুযায়ী Monk, Brian C., Keniya, Mikhail V.
প্রকাশিত J Fungi (Basel) (2021)

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

অনুযায়ী Rosam, Katharina, Monk, Brian C., Lackner, Michaela
প্রকাশিত J Fungi (Basel) (2020)

Linkage of Mutations Affecting minus Flagellar Membrane Agglutinability to the mt(-) Mating-Type Locus of Chlamydomonas

অনুযায়ী Hwang, Carol J., Monk, Brian C., Goodenough, Ursula W.
প্রকাশিত 1981

Morphotypic Conversion in Listeria monocytogenes Biofilm Formation: Biological Significance of Rough Colony Isolates

অনুযায়ী Monk, Ian R., Cook, Gregory M., Monk, Brian C., Bremer, Philip J.
প্রকাশিত 2004

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

অনুযায়ী Keniya, Mikhail V., Fleischer, Edmond, Klinger, Anette, Cannon, Richard D., Monk, Brian C.
প্রকাশিত PLoS One (2015)

Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase

অনুযায়ী Sagatova, Alia A., Keniya, Mikhail V., Tyndall, Joel D. A., Monk, Brian C.
প্রকাশিত Antimicrob Agents Chemother (2018)

Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery

অনুযায়ী Keniya, Mikhail V., Ruma, Yasmeen N., Tyndall, Joel D. A., Monk, Brian C.
প্রকাশিত Antimicrob Agents Chemother (2018)

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

অনুযায়ী Banerjee, Atanu, Pata, Jorgaq, Sharma, Suman, Monk, Brian C., Falson, Pierre, Prasad, Rajendra
প্রকাশিত J Fungi (Basel) (2021)

Fungal PDR transporters: phylogeny, topology, motifs and function

অনুযায়ী Lamping, Erwin, Baret, Philippe V., Holmes, Ann R., Monk, Brian C., Goffeau, Andre, Cannon, Richard D.
প্রকাশিত 2009

Heterologous expression of Candida albicans Pma1p in Saccharomyces cerevisiae

অনুযায়ী Keniya, Mikhail V., Cannon, Richard D., Nguyễn, ẤnBình, Tyndall, Joel D. A., Monk, Brian C.
প্রকাশিত FEMS Yeast Res (2013)

Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

অনুযায়ী Sagatova, Alia A., Keniya, Mikhail V., Wilson, Rajni K., Monk, Brian C., Tyndall, Joel D. A.
প্রকাশিত Antimicrob Agents Chemother (2015)

Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase

অনুযায়ী Caramalho, Rita, Tyndall, Joel D. A., Monk, Brian C., Larentis, Thomas, Lass-Flörl, Cornelia, Lackner, Michaela
প্রকাশিত Sci Rep (2017)

Identification of Nile Red as a fluorescent substrate of the Candida albicans ABC transporters Cdr1p and Cdr2p and the MFS transporter Mdr1p

অনুযায়ী Ivnitski-Steele, Irena, Holmes, Ann R, Lamping, Erwin, Monk, Brian C, Cannon, Richard D, Sklar, Larry A.
প্রকাশিত 2009

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

অনুযায়ী Sagatova, Alia A., Keniya, Mikhail V., Wilson, Rajni K., Sabherwal, Manya, Tyndall, Joel D. A., Monk, Brian C.
প্রকাশিত Sci Rep (2016)

The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida a...

অনুযায়ী Holmes, Ann R., Keniya, Mikhail V., Ivnitski-Steele, Irena, Monk, Brian C., Lamping, Erwin, Sklar, Larry A., Cannon, Richard D.
প্রকাশিত 2012

Characterization of Three Classes of Membrane Proteins Involved in Fungal Azole Resistance by Functional Hyperexpression in Saccharomyces cerevisiae

অনুযায়ী Lamping, Erwin, Monk, Brian C., Niimi, Kyoko, Holmes, Ann R., Tsao, Sarah, Tanabe, Koichi, Niimi, Masakazu, Uehara, Yoshimasa, Cannon, Richard D.
প্রকাশিত 2007

Crystal Structures of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery

অনুযায়ী Keniya, Mikhail V., Sabherwal, Manya, Wilson, Rajni K., Woods, Matthew A., Sagatova, Alia A., Tyndall, Joel D. A., Monk, Brian C.
প্রকাশিত Antimicrob Agents Chemother (2018)

Functional Expression of Candida albicans Drug Efflux Pump Cdr1p in a Saccharomyces cerevisiae Strain Deficient in Membrane Transporters

অনুযায়ী Nakamura, Kenjirou, Niimi, Masakazu, Niimi, Kyoko, Holmes, Ann R., Yates, Jenine E., Decottignies, Anabelle, Monk, Brian C., Goffeau, Andre, Cannon, Richard D.
প্রকাশিত 2001

ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates

অনুযায়ী Holmes, Ann R., Lin, Ya-Hsun, Niimi, Kyoko, Lamping, Erwin, Keniya, Mikhail, Niimi, Masakazu, Tanabe, Koichi, Monk, Brian C., Cannon, Richard D.
প্রকাশিত 2008

Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d-octapeptide derivative inhibitor

অনুযায়ী Niimi, Kyoko, Harding, David R. K., Holmes, Ann R., Lamping, Erwin, Niimi, Masakazu, Tyndall, Joel D. A., Cannon, Richard D., Monk, Brian C.
প্রকাশিত 2012