Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d-octapeptide derivative inhibitor

Over-expression of the Candida albicans ATP-binding cassette transporter CaCdr1p causes clinically significant resistance to azole drugs including fluconazole (FLC). Screening of a ~1.89 × 10(6) member d-octapeptide combinatorial library that concentrates library members at the yeast cell surface id...

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Main Authors: Niimi, Kyoko, Harding, David R. K., Holmes, Ann R., Lamping, Erwin, Niimi, Masakazu, Tyndall, Joel D. A., Cannon, Richard D., Monk, Brian C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418399/
https://ncbi.nlm.nih.gov/pubmed/22788839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08140.x
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