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Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d-octapeptide derivative inhibitor
Over-expression of the Candida albicans ATP-binding cassette transporter CaCdr1p causes clinically significant resistance to azole drugs including fluconazole (FLC). Screening of a ~1.89 × 10(6) member d-octapeptide combinatorial library that concentrates library members at the yeast cell surface id...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418399/ https://ncbi.nlm.nih.gov/pubmed/22788839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08140.x |
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