Functional Expression of Candida albicans Drug Efflux Pump Cdr1p in a Saccharomyces cerevisiae Strain Deficient in Membrane Transporters

Analysis of the transport functions of individual Candida albicans plasma membrane drug efflux pumps is hampered by the multitude of endogenous transporters. We have stably expressed C. albicans Cdr1p, the major pump implicated in multiple-drug-resistance phenotypes, from the genomic PDR5 locus in a...

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Detalhes bibliográficos
Main Authors: Nakamura, Kenjirou, Niimi, Masakazu, Niimi, Kyoko, Holmes, Ann R., Yates, Jenine E., Decottignies, Anabelle, Monk, Brian C., Goffeau, Andre, Cannon, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90839/
https://ncbi.nlm.nih.gov/pubmed/11709310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3366-3374.2001
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