Functional Expression of Candida albicans Drug Efflux Pump Cdr1p in a Saccharomyces cerevisiae Strain Deficient in Membrane Transporters

Analysis of the transport functions of individual Candida albicans plasma membrane drug efflux pumps is hampered by the multitude of endogenous transporters. We have stably expressed C. albicans Cdr1p, the major pump implicated in multiple-drug-resistance phenotypes, from the genomic PDR5 locus in a...

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Main Authors: Nakamura, Kenjirou, Niimi, Masakazu, Niimi, Kyoko, Holmes, Ann R., Yates, Jenine E., Decottignies, Anabelle, Monk, Brian C., Goffeau, Andre, Cannon, Richard D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90839/
https://ncbi.nlm.nih.gov/pubmed/11709310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3366-3374.2001
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