Chargement en cours...
Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase
Infections by fungal pathogens such as Candida albicans and Aspergillus fumigatus and their resistance to triazole drugs are major concerns. Fungal lanosterol 14α-demethylase belongs to the CYP51 class in the cytochrome P450 superfamily of enzymes. This monospanning bitopic membrane protein is invol...
Enregistré dans:
| Publié dans: | Antimicrob Agents Chemother |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505223/ https://ncbi.nlm.nih.gov/pubmed/26055382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00925-15 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|