Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

Multidrug resistance (MDR) transporters belonging to either the ATP-Binding Cassette (ABC) or Major Facilitator Superfamily (MFS) groups are major determinants of clinical drug resistance in fungi. The overproduction of these proteins enables the extrusion of incoming drugs at rates that prevent let...

Full description

Saved in:
Bibliographic Details
Published in:J Fungi (Basel)
Main Authors: Banerjee, Atanu, Pata, Jorgaq, Sharma, Suman, Monk, Brian C., Falson, Pierre, Prasad, Rajendra
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7908972/
https://ncbi.nlm.nih.gov/pubmed/33498218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof7020068
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items