Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

Multidrug resistance (MDR) transporters belonging to either the ATP-Binding Cassette (ABC) or Major Facilitator Superfamily (MFS) groups are major determinants of clinical drug resistance in fungi. The overproduction of these proteins enables the extrusion of incoming drugs at rates that prevent let...

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Detalles Bibliográficos
Publicado en:J Fungi (Basel)
Autores principales: Banerjee, Atanu, Pata, Jorgaq, Sharma, Suman, Monk, Brian C., Falson, Pierre, Prasad, Rajendra
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7908972/
https://ncbi.nlm.nih.gov/pubmed/33498218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof7020068
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