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Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans
Multidrug resistance (MDR) transporters belonging to either the ATP-Binding Cassette (ABC) or Major Facilitator Superfamily (MFS) groups are major determinants of clinical drug resistance in fungi. The overproduction of these proteins enables the extrusion of incoming drugs at rates that prevent let...
Guardat en:
| Publicat a: | J Fungi (Basel) |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7908972/ https://ncbi.nlm.nih.gov/pubmed/33498218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof7020068 |
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