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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance
OBJECTIVE: To identify a novel class of inhibitors of fungal transporters involved in drug resistance. METHODS: A series of structurally-related low molecular mass compounds was synthesized using combinatorial chemistry of a cyclobutene-dione (squarile) core. These compounds were screened for their...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423874/ https://ncbi.nlm.nih.gov/pubmed/25951180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126350 |
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