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Fungal PDR transporters: phylogeny, topology, motifs and function

The overexpression of pleiotropic drug resistance (PDR) efflux pumps of the ATP-binding cassette (ABC) transporter superfamily frequently correlates with multidrug resistance. Phylogenetic analysis of 349 full-size (~160 kDa) PDR proteins (Pdrps) from 55 fungal species, including major fungal pathog...

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Bibliografiske detaljer
Main Authors: Lamping, Erwin, Baret, Philippe V., Holmes, Ann R., Monk, Brian C., Goffeau, Andre, Cannon, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814995/
https://ncbi.nlm.nih.gov/pubmed/19857594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2009.10.007
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