Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem

Por Ward, Jeremy P.T., McMurtry, Ivan F.
Publicado em 2009

Hypoxia Impairs Vasodilation in the Lung

Por Voelkel, Norbert F., McMurtry, Ivan F., Reeves, John T.
Publicado em 1981

Role of endothelin-1 in lung disease

Por Fagan, Karen A, McMurtry, Ivan F, Rodman, David M
Publicado em 2001

Mitochondria in Hypoxic Pulmonary Vasoconstriction: Potential Importance of Compartmentalized Reactive Oxygen Species Signaling

Por Gillespie, Mark N., Al-Mehdi, Abu-Bakr, McMurtry, Ivan F.
Publicado em 2013

Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion

Por Zhou, Chun, Crockett, Edward S., Batten, Lynn, McMurtry, Ivan F., Stevens, Troy
Publicado no Am J Physiol Lung Cell Mol Physiol (2018)

S1P(4) receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs

Por Ota, Hiroki, Beutz, Michelle A., Ito, Masako, Abe, Kohtaro, Oka, Masahiko, McMurtry, Ivan F.
Publicado em 2011

Chronic hypoxia does not cause wall thickening of intra‐acinar pulmonary supernumerary arteries

Por Oshima, Kaori, McLendon, Jared M., Wagner, Wiltz W., McMurtry, Ivan F., Oka, Masahiko
Publicado no Physiol Rep (2016)

Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

Por Chettimada, Sukrutha, Gupte, Rakhee, Rawat, Dhwajbahadur, Gebb, Sarah A., McMurtry, Ivan F., Gupte, Sachin A.
Publicado no Am J Physiol Lung Cell Mol Physiol (2014)

Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH)

Por Rashid, Jahidur, Patel, Brijeshkumar, Nozik-Grayck, Eva, McMurtry, Ivan F., Stenmark, Kurt R, Ahsan, Fakhrul
Publicado no J Control Release (2017)

Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency

Por Gupta, Nilesh, Rashid, Jahidur, Nozik-Grayck, Eva, McMurtry, Ivan F., Stenmark, Kurt R., Ahsan, Fakhrul
Publicado no Mol Pharm (2017)

Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension

Por Hashimoto, Ryota, Joshi, Sachindra Raj, Jiang, Houli, Capdevila, Jorge H., McMurtry, Ivan F., Laniado Schwartzman, Michal, Gupte, Sachin A.
Publicado no Am J Physiol Heart Circ Physiol (2017)

Development of Occlusive Neointimal Lesions in Distal Pulmonary Arteries of Endothelin B Receptor–Deficient Rats: A New Model of Severe Pulmonary Arterial Hypertension

Por Ivy, D. Dunbar, McMurtry, Ivan F., Colvin, Kelley, Imamura, Masatoshi, Oka, Masahiko, Lee, Dong-Seok, Gebb, Sarah, Jones, Peter Lloyd
Publicado em 2005

Activation of Glucose-6-phosphate Dehydrogenase Promotes Acute Hypoxic Pulmonary Artery Contraction

Por Gupte, Rakhee S., Rawat, Dhawjbahadur K., Chettimada, Sukrutha, Cioffi, Donna L., Wolin, Michael S., Gerthoffer, William T., McMurtry, Ivan F., Gupte, Sachin A.
Publicado em 2010

Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension

Por Gairhe, Salina, Joshi, Sachindra R., Bastola, Mrigendra M., McLendon, Jared M., Oka, Masahiko, Fagan, Karen A., McMurtry, Ivan F.
Publicado no Pulm Circ (2016)

Platelet-Derived Growth Factor BB Induces Nuclear Export and Proteasomal Degradation of CREB via Phosphatidylinositol 3-Kinase/Akt Signaling in Pulmonary Artery Smooth Muscle Cells

Por Garat, Chrystelle V., Fankell, Dana, Erickson, Paul F., Reusch, Jane E.-B., Bauer, Natalie N., McMurtry, Ivan F., Klemm, Dwight J.
Publicado em 2006

Liposomal Fasudil, a Rho-Kinase Inhibitor, for Prolonged Pulmonary Preferential Vasodilation in Pulmonary Arterial Hypertension

Por Gupta, Vivek, Gupta, Nilesh, Shaik, Imam H., Mehvar, Reza, McMurtry, Ivan F., Oka, Masahiko, Nozik-Grayck, Eva, Komatsu, Masanobu, Ahsan, Fakhrul
Publicado em 2013

Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats

Por Toba, Michie, Alzoubi, Abdallah, O'Neill, Kealan D., Gairhe, Salina, Matsumoto, Yuri, Oshima, Kaori, Abe, Kohtaro, Oka, Masahiko, McMurtry, Ivan F.
Publicado em 2013

Inhaled PLGA Particles of Prostaglandin E(1) Ameliorate Symptoms and Progression of Pulmonary Hypertension at a Reduced Dosing Frequency

Por Gupta, Vivek, Gupta, Nilesh, Shaik, Imam H., Mehvar, Reza, Nozik-Grayck, Eva, McMurtry, Ivan F., Oka, Masahiko, Komatsu, Masanobu, Ahsan, Fakhrul
Publicado em 2013

Peptide-Coated Liposomal Fasudil Enhances Site Specific Vasodilation in Pulmonary Arterial Hypertension

Por Nahar, Kamrun, Absar, Shahriar, Gupta, Nilesh, Kotamraju, Venkata Ramana, McMurtry, Ivan F., Oka, Masahiko, Komatsu, Masanobu, Nozik-Grayck, Eva, Ahsan, Fakhrul
Publicado no Mol Pharm (2014)

Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension

Por Tanaka, Mariko, Abe, Kohtaro, Oka, Masahiko, Saku, Keita, Yoshida, Keimei, Ishikawa, Tomohito, McMurtry, Ivan F., Sunagawa, Kenji, Hoka, Sumio, Tsutsui, Hiroyuki
Publicado no Physiol Rep (2017)