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Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension

Abstract. Despite several advances in the pathobiology of pulmonary arterial hypertension (PAH), its pathogenesis is not completely understood. Current therapy improves symptoms but has disappointing effects on survival. Sphingosine-1-phosphate (S1P) is a lysophospholipid synthesized by sphingosine...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Gairhe, Salina, Joshi, Sachindra R., Bastola, Mrigendra M., McLendon, Jared M., Oka, Masahiko, Fagan, Karen A., McMurtry, Ivan F.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019090/
https://ncbi.nlm.nih.gov/pubmed/27683614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/687766
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