MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension.

Heart failure, a major cause of morbidity and mortality in patients with pulmonary arterial hypertension (PAH), is an outcome of complex biochemical processes. In this study, we determined changes in microRNAs (miRs) in the right and left ventricles of normal and PAH rats. Using an unbiased quantita...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Joshi, Sachindra Raj, Dhagia, Vidhi, Gairhe, Salina, Edwards, John G., McMurtry, Ivan F., Gupte, Sachin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199238/
https://ncbi.nlm.nih.gov/pubmed/27422986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00264.2016
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