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MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension.

Heart failure, a major cause of morbidity and mortality in patients with pulmonary arterial hypertension (PAH), is an outcome of complex biochemical processes. In this study, we determined changes in microRNAs (miRs) in the right and left ventricles of normal and PAH rats. Using an unbiased quantita...

詳細記述

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書誌詳細
出版年:Am J Physiol Heart Circ Physiol
主要な著者: Joshi, Sachindra Raj, Dhagia, Vidhi, Gairhe, Salina, Edwards, John G., McMurtry, Ivan F., Gupte, Sachin A.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199238/
https://ncbi.nlm.nih.gov/pubmed/27422986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00264.2016
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