Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension

Pulmonary hypertension (PH) is a multicellular and progressive disease with a high mortality rate. Among many cell types, hematopoietic stem cells (HSCs) are incriminated in the pathogenesis of PH. However, our understanding of the mechanisms that increase HSCs in blood and lungs of hypertensive ani...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Hashimoto, Ryota, Lanier, Gregg M., Dhagia, Vidhi, Joshi, Sachindra R., Jordan, Allan, Waddell, Ian, Tuder, Rubin, Stenmark, Kurt R., Wolin, Michael S., McMurtry, Ivan F., Gupte, Sachin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052680/
https://ncbi.nlm.nih.gov/pubmed/31913656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00327.2019
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