Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice

Abstract. Epoxyeicosatrienoicacids (EETs), synthesized from arachidonic acid by epoxygenases of the CYP2C and CYP2J gene subfamilies, contribute to hypoxic pulmonary vasoconstriction (HPV) in mice. Despite their roles in HPV, it is controversial whether EETs mediate or ameliorate pulmonary hypertens...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pulm Circ
Prif Awduron: Joshi, Sachindra Raj, Lakhkar, Anand, Dhagia, Vidhi, Zias, Ariadne L., Soldatos, Vasiliki, Oshima, Kaori, Jiang, Houli, Gotlinger, Katherine, Capdevila, Jorge H., Schwartzman, Michal L., McMurtry, Ivan F., Gupte, Sachin A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: University of Chicago Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019089/
https://ncbi.nlm.nih.gov/pubmed/27683613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/688060
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