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Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice
Abstract. Epoxyeicosatrienoicacids (EETs), synthesized from arachidonic acid by epoxygenases of the CYP2C and CYP2J gene subfamilies, contribute to hypoxic pulmonary vasoconstriction (HPV) in mice. Despite their roles in HPV, it is controversial whether EETs mediate or ameliorate pulmonary hypertens...
Gorde:
| Argitaratua izan da: | Pulm Circ |
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| Egile Nagusiak: | , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
University of Chicago Press
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5019089/ https://ncbi.nlm.nih.gov/pubmed/27683613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/688060 |
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