Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice

Abstract. Epoxyeicosatrienoicacids (EETs), synthesized from arachidonic acid by epoxygenases of the CYP2C and CYP2J gene subfamilies, contribute to hypoxic pulmonary vasoconstriction (HPV) in mice. Despite their roles in HPV, it is controversial whether EETs mediate or ameliorate pulmonary hypertens...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pulm Circ
Egile Nagusiak: Joshi, Sachindra Raj, Lakhkar, Anand, Dhagia, Vidhi, Zias, Ariadne L., Soldatos, Vasiliki, Oshima, Kaori, Jiang, Houli, Gotlinger, Katherine, Capdevila, Jorge H., Schwartzman, Michal L., McMurtry, Ivan F., Gupte, Sachin A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: University of Chicago Press 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019089/
https://ncbi.nlm.nih.gov/pubmed/27683613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/688060
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