PPARα Ligands as Antitumorigenic and Antiangiogenic Agents

Por Pozzi, Ambra, Capdevila, Jorge H.
Publicado em 2008

Preparation of N-(t)Boc L-glutathione dimethyl and di-tert-butyl esters: versatile synthetic building blocks

Por Falck, J. R., Sangras, Bhavani, Capdevila, Jorge H.
Publicado em 2006

Arachidonic Acid Monooxygenase: Genetic and Biochemical Approaches to Physiological/Pathophysiological Relevance

Por Capdevila, Jorge H., Wang, Wenhui, Falck, John R.
Publicado no Prostaglandins Other Lipid Mediat (2015)

The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis ()

Por Yang, Shiling, Wei, Shouzou, Pozzi, Ambra, Capdevila, Jorge H.
Publicado em 2009

The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading

Por Holla, Vijaykumar R., Makita, Keiko, Zaphiropoulos, Peter G., Capdevila, Jorge H.
Publicado em 1999

Increased Renal Proximal Convoluted Tubule Transport Contributes to Hypertension in Cyp4a14 Knockout Mice

Por Quigley, Raymond, Chakravarty, Sumana, Zhao, Xueying, Imig, John D., Capdevila, Jorge H.
Publicado em 2009

Convenient syntheses of [20,20,20-(2)H(3)]-arachidonic acid and [20,20-(2)H(2)]-20-hydroxyeicosatetraenoic acid

Por Falck, J. R., Anjaiah, Siddam, Tuniki, Venugopal Raju, Gopal, V. Raj, Capdevila, Jorge H.
Publicado em 2006

Mitogenic Activity and Signaling Mechanism of 2-(14,15- Epoxyeicosatrienoyl)Glycerol, a Novel Cytochrome P450 Arachidonate Metabolite

Por Chen, Jianchun, Chen, Jian-Kang, Falck, John R., Anjaiah, Siddam, Capdevila, Jorge H., Harris, Raymond C.
Publicado em 2007

Epoxyeicosatrienoic Acids (EETs) Regulate Epithelial Sodium Channel Activity by Extracellular Signal-regulated Kinase 1/2 (ERK1/2)-mediated Phosphorylation

Por Pidkovka, Nataliya, Rao, Reena, Mei, Shaojun, Gong, Yan, Harris, Raymond C., Wang, Wen-Hui, Capdevila, Jorge H.
Publicado em 2013

Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney

Por Zhang, Ming-Zhi, Wang, Yinqiu, Yao, Bing, Gewin, Leslie, Wei, Shouzuo, Capdevila, Jorge H., Harris, Raymond C.
Publicado em 2013

Mitogenic Activity and Signaling Mechanism of 2-(14,15-Epoxyeicosatrienoyl)Glycerol, a Novel Cytochrome P450 Arachidonate Metabolite

Por Chen, Jianchun, Chen, Jian-Kang, Falck, John R., Guthi, Jagadeesh Setti, Anjaiah, Siddam, Capdevila, Jorge H., Harris, Raymond C.
Publicado em 2007

Association of a CYP4A11 Variant and Blood Pressure in Black Men

Por Gainer, James V., Lipkowitz, Michael S., Yu, Chang, Waterman, Michael R., Dawson, Elliott P., Capdevila, Jorge H., Brown, Nancy J.
Publicado em 2008

The Anti-tumorigenic Properties of Peroxisomal Proliferator-activated Receptor α Are Arachidonic Acid Epoxygenase-mediated

Por Pozzi, Ambra, Popescu, Vlad, Yang, Shilin, Mei, Shaojun, Shi, Mingjian, Puolitaival, Satu M., Caprioli, Richard M., Capdevila, Jorge H.
Publicado em 2010

Cyp2c44 epoxygenase in the collecting duct is essential for the high K(+) intake-induced antihypertensive effect

Por Wang, Wen-Hui, Zhang, Chengbiao, Lin, Dao-Hong, Wang, Lijun, Graves, Joan P., Zeldin, Darryl C., Capdevila, Jorge H.
Publicado em 2014

20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOR...

Por Savas, Üzen, Wei, Shouzou, Hsu, Mei-Hui, Falck, John R., Guengerich, F. Peter, Capdevila, Jorge H., Johnson, Eric F.
Publicado no J Biol Chem (2016)

The Cyp2c44 Epoxygenase Regulates Epithelial Sodium Channel Activity and the Blood Pressure Responses to Increased Dietary Salt

Por Capdevila, Jorge H., Pidkovka, Nataliya, Mei, Shaojun, Gong, Yan, Falck, John R., Imig, John D., Harris, Raymond C., Wang, Wenhui
Publicado em 2014

The T8590C Polymorphism of CYP4A11 and 20-Hydroxyeicosatetraenoic Acid in Essential Hypertension

Por Laffer, Cheryl L., Gainer, James V., Waterman, Michael R., Capdevila, Jorge H., Laniado-Schwartzman, Michal, Nasjletti, Alberto, Brown, Nancy J., Elijovich, Fernando
Publicado em 2008

Identification of Novel Endogenous Cytochrome P450 Arachidonate Metabolites with High Affinity for Cannabinoid Receptors

Por Chen, Jian-Kang, Chen, Jianchun, Imig, John D., Wei, Shouzuo, Hachey, David L., Guthi, Jagadeesh Setti, Falck, John R., Capdevila, Jorge H., Harris, Raymond C.
Publicado em 2008

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications

Por Falck, John R., Koduru, Sreenivasulu Reddy, Mohapatra, Seetaram, Manne, Rajkumar, Atcha, Raju, Manthati, Vijaya L., Capdevila, Jorge H., Christian, Sarah, Imig, John D., Campbell, William B.
Publicado em 2014

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension

Por Ding, Yan, Wu, Cheng-Chia, Garcia, Victor, Dimitrova, Irina, Weidenhammer, Adam, Joseph, Gregory, Zhang, Frank, Manthati, Vijay L., Falck, John R., Capdevila, Jorge H., Schwartzman, Michal L.
Publicado em 2013