Activation of Glucose-6-phosphate Dehydrogenase Promotes Acute Hypoxic Pulmonary Artery Contraction

Hypoxic pulmonary vasoconstriction (HPV) is a physiological response to a decrease in airway O(2) tension, but the underlying mechanism is incompletely understood. We studied the contribution of glucose-6-phosphate dehydrogenase (Glc-6-PD), an important regulator of NADPH redox and production of rea...

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Detalhes bibliográficos
Main Authors: Gupte, Rakhee S., Rawat, Dhawjbahadur K., Chettimada, Sukrutha, Cioffi, Donna L., Wolin, Michael S., Gerthoffer, William T., McMurtry, Ivan F., Gupte, Sachin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885235/
https://ncbi.nlm.nih.gov/pubmed/20363753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092916
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