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Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133(+) progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats
Although hypoxia is detrimental to most cell types, it aids survival of progenitor cells and is associated with diseases like cancer and pulmonary hypertension in humans. Therefore, understanding the underlying mechanisms that promote survival of progenitor cells in hypoxia and then developing novel...
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| Pubblicato in: | Am J Physiol Lung Cell Mol Physiol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199226/ https://ncbi.nlm.nih.gov/pubmed/25063801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00303.2013 |
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