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Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133(+) progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats

Although hypoxia is detrimental to most cell types, it aids survival of progenitor cells and is associated with diseases like cancer and pulmonary hypertension in humans. Therefore, understanding the underlying mechanisms that promote survival of progenitor cells in hypoxia and then developing novel...

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Опубликовано в: :Am J Physiol Lung Cell Mol Physiol
Главные авторы: Chettimada, Sukrutha, Joshi, Sachindra Raj, Alzoubi, Abdallah, Gebb, Sarah A., McMurtry, Ivan F., Gupte, Rakhee, Gupte, Sachin A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199226/
https://ncbi.nlm.nih.gov/pubmed/25063801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00303.2013
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