Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency

Homeostatic control of vascular smooth muscle cell (VSMC) differentiation is critical for contractile activity and regulation of blood flow. Recently, we reported that precontracted blood vessels are relaxed and the phenotype of VSMC is regulated from a synthetic to contractile state by glucose-6-ph...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Chettimada, Sukrutha, Joshi, Sachindra Raj, Dhagia, Vidhi, Aiezza, Alessandro, Lincoln, Thomas M., Gupte, Rakhee, Miano, Joseph M., Gupte, Sachin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114469/
https://ncbi.nlm.nih.gov/pubmed/27521420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00335.2016
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