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Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency

Homeostatic control of vascular smooth muscle cell (VSMC) differentiation is critical for contractile activity and regulation of blood flow. Recently, we reported that precontracted blood vessels are relaxed and the phenotype of VSMC is regulated from a synthetic to contractile state by glucose-6-ph...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Chettimada, Sukrutha, Joshi, Sachindra Raj, Dhagia, Vidhi, Aiezza, Alessandro, Lincoln, Thomas M., Gupte, Rakhee, Miano, Joseph M., Gupte, Sachin A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114469/
https://ncbi.nlm.nih.gov/pubmed/27521420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00335.2016
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