Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension

Pulmonary hypertension (PH) is a multicellular and progressive disease with a high mortality rate. Among many cell types, hematopoietic stem cells (HSCs) are incriminated in the pathogenesis of PH. However, our understanding of the mechanisms that increase HSCs in blood and lungs of hypertensive ani...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Hashimoto, Ryota, Lanier, Gregg M., Dhagia, Vidhi, Joshi, Sachindra R., Jordan, Allan, Waddell, Ian, Tuder, Rubin, Stenmark, Kurt R., Wolin, Michael S., McMurtry, Ivan F., Gupte, Sachin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052680/
https://ncbi.nlm.nih.gov/pubmed/31913656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00327.2019
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