Role of the Aryl Hydrocarbon Receptor in Sugen 5416–induced Experimental Pulmonary Hypertension

Rats dosed with the vascular endothelial growth factor inhibitor Sugen 5416 (Su), subjected to hypoxia, and then restored to normoxia have become a widely used model of pulmonary arterial hypertension (PAH). However, the mechanism by which Su exacerbates pulmonary hypertension is unclear. We investi...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Cell Mol Biol
Asıl Yazarlar: Dean, Afshan, Gregorc, Teja, Docherty, Craig K., Harvey, Katie Y., Nilsen, Margaret, Morrell, Nicholas W., MacLean, Margaret R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854960/
https://ncbi.nlm.nih.gov/pubmed/28956952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0260OC
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