Role of the Aryl Hydrocarbon Receptor in Sugen 5416–induced Experimental Pulmonary Hypertension

Rats dosed with the vascular endothelial growth factor inhibitor Sugen 5416 (Su), subjected to hypoxia, and then restored to normoxia have become a widely used model of pulmonary arterial hypertension (PAH). However, the mechanism by which Su exacerbates pulmonary hypertension is unclear. We investi...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Dean, Afshan, Gregorc, Teja, Docherty, Craig K., Harvey, Katie Y., Nilsen, Margaret, Morrell, Nicholas W., MacLean, Margaret R.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854960/
https://ncbi.nlm.nih.gov/pubmed/28956952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0260OC
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