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The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up

Abstract. The combination of a vascular endothelial growth factor receptor antagonist, Sugen 5416 (SU5416), and chronic hypoxia is known to cause pronounced pulmonary hypertension (PH) with angioobliterative lesions in rats and leads to exaggerated PH in mice as well. We sought to determine whether...

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Bibliografiske detaljer
Udgivet i:Pulm Circ
Main Authors: Vitali, Sally H., Hansmann, Georg, Rose, Chase, Fernandez-Gonzalez, Angeles, Scheid, Annette, Mitsialis, S. Alex, Kourembanas, Stella
Format: Artigo
Sprog:Inglês
Udgivet: University of Chicago Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278622/
https://ncbi.nlm.nih.gov/pubmed/25610598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/678508
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