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The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up

Abstract. The combination of a vascular endothelial growth factor receptor antagonist, Sugen 5416 (SU5416), and chronic hypoxia is known to cause pronounced pulmonary hypertension (PH) with angioobliterative lesions in rats and leads to exaggerated PH in mice as well. We sought to determine whether...

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Bibliographische Detailangaben
Veröffentlicht in:Pulm Circ
Hauptverfasser: Vitali, Sally H., Hansmann, Georg, Rose, Chase, Fernandez-Gonzalez, Angeles, Scheid, Annette, Mitsialis, S. Alex, Kourembanas, Stella
Format: Artigo
Sprache:Inglês
Veröffentlicht: University of Chicago Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278622/
https://ncbi.nlm.nih.gov/pubmed/25610598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/678508
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