Role of the Aryl Hydrocarbon Receptor in Sugen 5416–induced Experimental Pulmonary Hypertension

Rats dosed with the vascular endothelial growth factor inhibitor Sugen 5416 (Su), subjected to hypoxia, and then restored to normoxia have become a widely used model of pulmonary arterial hypertension (PAH). However, the mechanism by which Su exacerbates pulmonary hypertension is unclear. We investi...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Dean, Afshan, Gregorc, Teja, Docherty, Craig K., Harvey, Katie Y., Nilsen, Margaret, Morrell, Nicholas W., MacLean, Margaret R.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854960/
https://ncbi.nlm.nih.gov/pubmed/28956952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0260OC
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