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S1P(4) receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs

This study aimed to identify receptors mediating sphingosine-1-phosphate (S1P)-induced vasoconstriction in the normotensive and chronic hypoxia-induced hypertensive rat pulmonary circulation. In isolated perfused lungs from normoxic rats, infusion of S1P caused a sustained vasoconstriction, which wa...

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Main Authors: Ota, Hiroki, Beutz, Michelle A., Ito, Masako, Abe, Kohtaro, Oka, Masahiko, McMurtry, Ivan F.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224432/
https://ncbi.nlm.nih.gov/pubmed/22140630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.87309
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