Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension

It is widely accepted that impaired bioavailability of endothelial nitric oxide (NO) plays a critical role in the pathophysiology of pulmonary arterial hypertension (PAH). However, there are published data that show that relatively many PAH patients respond favorably to acetylcholine‐induced pulmona...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Tanaka, Mariko, Abe, Kohtaro, Oka, Masahiko, Saku, Keita, Yoshida, Keimei, Ishikawa, Tomohito, McMurtry, Ivan F., Sunagawa, Kenji, Hoka, Sumio, Tsutsui, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727286/
https://ncbi.nlm.nih.gov/pubmed/29208691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13537
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