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Inhaled PLGA Particles of Prostaglandin E(1) Ameliorate Symptoms and Progression of Pulmonary Hypertension at a Reduced Dosing Frequency

This study sought to investigate the efficacy of a noninvasive and long acting polymeric particle based formulation of prostaglandin E(1) (PGE(1)), a potent pulmonary vasodilator, in alleviating the signs of pulmonary hypertension (PH) and reversing the biochemical changes that occur in the diseased...

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Detalhes bibliográficos
Main Authors: Gupta, Vivek, Gupta, Nilesh, Shaik, Imam H., Mehvar, Reza, Nozik-Grayck, Eva, McMurtry, Ivan F., Oka, Masahiko, Komatsu, Masanobu, Ahsan, Fakhrul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096561/
https://ncbi.nlm.nih.gov/pubmed/23485062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300426u
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