Peptide-Coated Liposomal Fasudil Enhances Site Specific Vasodilation in Pulmonary Arterial Hypertension

[Image: see text] This study sought to develop a liposomal delivery system of fasudil—an investigational drug for the treatment of pulmonary arterial hypertension (PAH)—that will preferentially accumulate in the PAH lungs. Liposomal fasudil was prepared by film-hydration method, and the drug was enc...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Nahar, Kamrun, Absar, Shahriar, Gupta, Nilesh, Kotamraju, Venkata Ramana, McMurtry, Ivan F., Oka, Masahiko, Komatsu, Masanobu, Nozik-Grayck, Eva, Ahsan, Fakhrul
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255731/
https://ncbi.nlm.nih.gov/pubmed/25333706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500456k
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