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Cell Permeable Peptide Conjugated Nanoerythrosomes of Fasudil Prolong Pulmonary Arterial Vasodilation in PAH Rats

In this study, we tested the hypothesis that a cell permeable peptide, CARSKNKDC (CAR), conjugated nanoerythrosomes (NERs) containing fasudil, a rho-kinase (ROCK) inhibitor, produces prolonged pulmonary preferential vasodilation. CAR conjugated NERs containing fasudil were prepared by hypotonic lysi...

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Bibliografiske detaljer
Udgivet i:Eur J Pharm Biopharm
Main Authors: Gupta, Nilesh, Patel, Brijeshkumar, Nahar, Kamrun, Ahsan, Fakhrul
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293309/
https://ncbi.nlm.nih.gov/pubmed/25460151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2014.10.012
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