DNaseI Hypersensitivity and Ultraconservation Reveal Novel, Interdependent Long-Range Enhancers at the Complex Pax6 Cis-Regulatory Region

by McBride, David J., Buckle, Adam, van Heyningen, Veronica, Kleinjan, Dirk A.
Published 2011

Ku Heterodimer-Independent End Joining in Trypanosoma brucei Cell Extracts Relies upon Sequence Microhomology

by Burton, Peter, McBride, David J., Wilkes, Jonathan M., Barry, J. David, McCulloch, Richard
Published 2007

Detection of ctDNA in plasma of patients with clinically localised prostate cancer is associated with rapid disease progression

by Lau, Edmund, McCoy, Patrick, Reeves, Fairleigh, Chow, Ken, Clarkson, Michael, Kwan, Edmond M., Packwood, Kate, Northen, Helen, He, Miao, Kingsbury, Zoya, Mangiola, Stefano, Kerger, Michael, Furrer, Marc A., Crowe, Helen, Costello, Anthony J., McBride, David J., Ross, Mark T., Pope, Bernard, Hovens, Christopher M., Corcoran, Niall M.
Published in Genome Med (2020)

Use of Cancer-Specific Genomic Rearrangements to Quantify Disease Burden in Plasma from Patients with Solid Tumors

by McBride, David J., Orpana, Arto K., Sotiriou, Christos, Joensuu, Heikki, Stephens, Philip J., Mudie, Laura J., Hämälaïnen, Eija, Stebbings, Lucy A., Andersson, Leif C., Flanagan, Adrienne M., Durbecq, Virginie, Ignatiadis, Michail, Kallioniemi, Olli, Heckman, Caroline A., Alitalo, Kari, Edgren, Henrik, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Published 2010

A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma

by Sivanand, Sharanya, Peña-Llopis, Samuel, Zhao, Hong, Kucejova, Blanka, Spence, Patrick, Pavia-Jimenez, Andrea, Yamasaki, Toshinari, McBride, David J., Gillen, Jessica, Wolff, Nicholas C., Morlock, Lorraine, Lotan, Yair, Raj, Ganesh V., Sagalowsky, Arthur, Margulis, Vitaly, Cadeddu, Jeffrey A., Ross, Mark T., Bentley, David R., Kabbani, Wareef, Xie, Xian-Jin, Kapur, Payal, Williams, Noelle S., Brugarolas, James
Published 2012

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

by McBride, David J, Etemadmoghadam, Dariush, Cooke, Susanna L, Alsop, Kathryn, George, Joshy, Butler, Adam, Cho, Juok, Galappaththige, Danushka, Greenman, Chris, Howarth, Karen D, Lau, King W, Ng, Charlotte K, Raine, Keiran, Teague, Jon, Wedge, David C, Cancer Study Group, Australian Ovarian, Caubit, Xavier, Stratton, Michael R, Brenton, James D, Campbell, Peter J, Futreal, P Andrew, Bowtell, David DL
Published 2012

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

by Voet, Thierry, Kumar, Parveen, Van Loo, Peter, Cooke, Susanna L., Marshall, John, Lin, Meng-Lay, Zamani Esteki, Masoud, Van der Aa, Niels, Mateiu, Ligia, McBride, David J., Bignell, Graham R., McLaren, Stuart, Teague, Jon, Butler, Adam, Raine, Keiran, Stebbings, Lucy A., Quail, Michael A., D’Hooghe, Thomas, Moreau, Yves, Futreal, P. Andrew, Stratton, Michael R., Vermeesch, Joris R., Campbell, Peter J.
Published 2013

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

by Campbell, Peter J, Yachida, Shinichi, Mudie, Laura J, Stephens, Philip J, Pleasance, Erin D, Stebbings, Lucy A, Morsberger, Laura A, Latimer, Calli, McLaren, Stuart, Lin, Meng-Lay, McBride, David J, Varela, Ignacio, Nik-Zainal, Serena A, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P, Teague, Jon W, Griffin, Constance A, Burton, John, Swerdlow, Harold, Quail, Michael A, Stratton, Michael R, Iacobuzio-Donahue, Christine, Futreal, P Andrew
Published 2010

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

by Stephens, Philip J., Greenman, Chris D., Fu, Beiyuan, Yang, Fengtang, Bignell, Graham R., Mudie, Laura J., Pleasance, Erin D., Lau, King Wai, Beare, David, Stebbings, Lucy A., McLaren, Stuart, Lin, Meng-Lay, McBride, David J., Varela, Ignacio, Nik-Zainal, Serena, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Quail, Michael A., Burton, John, Swerdlow, Harold, Carter, Nigel P., Morsberger, Laura A., Iacobuzio-Donahue, Christine, Follows, George A., Green, Anthony R., Flanagan, Adrienne M., Stratton, Michael R., Futreal, P. Andrew, Campbell, Peter J.
Published 2011

COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES

by Stephens, Philip J, McBride, David J, Lin, Meng-Lay, Varela, Ignacio, Pleasance, Erin D, Simpson, Jared T, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Mudie, Laura J, Greenman, Chris D, Jia, Mingming, Latimer, Calli, Teague, Jon W, Lau, King Wai, Burton, John, Quail, Michael A, Swerdlow, Harold, Churcher, Carol, Natrajan, Rachael, Sieuwerts, Anieta M, Martens, John WM, Silver, Daniel P, Langerod, Anita, Russnes, Hege EG, Foekens, John A, Reis-Filho, Jorge S, van ’t Veer, Laura, Richardson, Andrea L, Børreson-Dale, Anne-Lise, Campbell, Peter J, Futreal, P Andrew, Stratton, Michael R
Published 2009

Whole exome sequencing of adenoid cystic carcinoma

by Stephens, Philip J., Davies, Helen R., Mitani, Yoshitsugu, Van Loo, Peter, Shlien, Adam, Tarpey, Patrick S., Papaemmanuil, Elli, Cheverton, Angela, Bignell, Graham R., Butler, Adam P., Gamble, John, Gamble, Stephen, Hardy, Claire, Hinton, Jonathan, Jia, Mingming, Jayakumar, Alagu, Jones, David, Latimer, Calli, McLaren, Stuart, McBride, David J., Menzies, Andrew, Mudie, Laura, Maddison, Mark, Raine, Keiran, Nik-Zainal, Serena, O’Meara, Sarah, Teague, Jon W., Varela, Ignacio, Wedge, David C., Whitmore, Ian, Lippman, Scott M., McDermott, Ultan, Stratton, Michael R., Campbell, Peter J., El-Naggar, Adel K., Futreal, P. Andrew
Published 2013

A small cell lung cancer genome reports complex tobacco exposure signatures

by Pleasance, Erin D, Stephens, Philip J, O'Meara, Sarah, McBride, David J, Meynert, Alison, Jones, David, Lin, Meng-Lay, Beare, David, Lau, King Wai, Greenman, Chris, Varela, Ignacio, Nik-Zainal, Serena, Davies, Helen R, Ordoñez, Gonzalo R, Mudie, Laura J, Latimer, Calli, Edkins, Sarah, Stebbings, Lucy, Chen, Lina, Jia, Mingming, Leroy, Catherine, Marshall, John, Menzies, Andrew, Butler, Adam, Teague, Jon W, Mangion, Jonathon, Sun, Yongming A, McLaughlin, Stephen F, Peckham, Heather E, Tsung, Eric F, Costa, Gina L, Lee, Clarence C, Minna, John D, Gazdar, Adi, Birney, Ewan, Rhodes, Michael D, McKernan, Kevin J, Stratton, Michael R, Futreal, P Andrew, Campbell, Peter J
Published 2009

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

by Dalgliesh, Gillian L., Furge, Kyle, Greenman, Chris, Chen, Lina, Bignell, Graham, Butler, Adam, Davies, Helen, Edkins, Sarah, Hardy, Claire, Latimer, Calli, Teague, Jon, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J., Forbes, Simon, Jia, Mingming, Jones, David, Knott, Henry, Kok, Chai Yin, Lau, King Wai, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maguire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Mulderrig, Lee, Mudie, Laura, O’Meara, Sarah, Pleasance, Erin, Rajasingham, Arjunan, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turrell, Kelly, Dykema, Karl J., Khoo, Sok Kean, Petillo, David, Wondergem, Bill, Anema, John, Kahnoski, Richard J., Teh, Bin Tean, Stratton, Michael R., Futreal, P. Andrew
Published 2010

A comprehensive catalogue of somatic mutations from a human cancer genome

by Pleasance, Erin D., Cheetham, R. Keira, Stephens, Philip J., McBride, David J., Humphray, Sean J., Greenman, Chris D., Varela, Ignacio, Lin, Meng-Lay, Ordóñez, Gonzalo R., Bignell, Graham R., Ye, Kai, Alipaz, Julie, Bauer, Markus J., Beare, David, Butler, Adam, Carter, Richard J., Chen, Lina, Cox, Anthony J., Edkins, Sarah, Kokko-Gonzales, Paula I., Gormley, Niall A., Grocock, Russell J., Haudenschild, Christian D., Hims, Matthew M., James, Terena, Jia, Mingming, Kingsbury, Zoya, Leroy, Catherine, Marshall, John, Menzies, Andrew, Mudie, Laura J., Ning, Zemin, Royce, Tom, Schulz-Trieglaff, Ole B., Spiridou, Anastassia, Stebbings, Lucy A., Szajkowski, Lukasz, Teague, Jon, Williamson, David, Chin, Lynda, Ross, Mark T., Campbell, Peter J., Bentley, David R., Futreal, P. Andrew, Stratton, Michael R.
Published 2009

The Life History of 21 Breast Cancers

by Nik-Zainal, Serena, Van Loo, Peter, Wedge, David C., Alexandrov, Ludmil B., Greenman, Christopher D., Lau, King Wai, Raine, Keiran, Jones, David, Marshall, John, Ramakrishna, Manasa, Shlien, Adam, Cooke, Susanna L., Hinton, Jonathan, Menzies, Andrew, Stebbings, Lucy A., Leroy, Catherine, Jia, Mingming, Rance, Richard, Mudie, Laura J., Gamble, Stephen J., Stephens, Philip J., McLaren, Stuart, Tarpey, Patrick S., Papaemmanuil, Elli, Davies, Helen R., Varela, Ignacio, McBride, David J., Bignell, Graham R., Leung, Kenric, Butler, Adam P., Teague, Jon W., Martin, Sancha, Jönsson, Goran, Mariani, Odette, Boyault, Sandrine, Miron, Penelope, Fatima, Aquila, Langerød, Anita, Aparicio, Samuel A.J.R., Tutt, Andrew, Sieuwerts, Anieta M., Borg, Åke, Thomas, Gilles, Salomon, Anne Vincent, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Published 2012

Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer

by Murchison, Elizabeth P., Schulz-Trieglaff, Ole B., Ning, Zemin, Alexandrov, Ludmil B., Bauer, Markus J., Fu, Beiyuan, Hims, Matthew, Ding, Zhihao, Ivakhno, Sergii, Stewart, Caitlin, Ng, Bee Ling, Wong, Wendy, Aken, Bronwen, White, Simon, Alsop, Amber, Becq, Jennifer, Bignell, Graham R., Cheetham, R. Keira, Cheng, William, Connor, Thomas R., Cox, Anthony J., Feng, Zhi-Ping, Gu, Yong, Grocock, Russell J., Harris, Simon R., Khrebtukova, Irina, Kingsbury, Zoya, Kowarsky, Mark, Kreiss, Alexandre, Luo, Shujun, Marshall, John, McBride, David J., Murray, Lisa, Pearse, Anne-Maree, Raine, Keiran, Rasolonjatovo, Isabelle, Shaw, Richard, Tedder, Philip, Tregidgo, Carolyn, Vilella, Albert J., Wedge, David C., Woods, Gregory M., Gormley, Niall, Humphray, Sean, Schroth, Gary, Smith, Geoffrey, Hall, Kevin, Searle, Stephen M.J., Carter, Nigel P., Papenfuss, Anthony T., Futreal, P. Andrew, Campbell, Peter J., Yang, Fengtang, Bentley, David R., Evers, Dirk J., Stratton, Michael R.
Published 2012

Mutational Processes Molding the Genomes of 21 Breast Cancers

by Nik-Zainal, Serena, Alexandrov, Ludmil B., Wedge, David C., Van Loo, Peter, Greenman, Christopher D., Raine, Keiran, Jones, David, Hinton, Jonathan, Marshall, John, Stebbings, Lucy A., Menzies, Andrew, Martin, Sancha, Leung, Kenric, Chen, Lina, Leroy, Catherine, Ramakrishna, Manasa, Rance, Richard, Lau, King Wai, Mudie, Laura J., Varela, Ignacio, McBride, David J., Bignell, Graham R., Cooke, Susanna L., Shlien, Adam, Gamble, John, Whitmore, Ian, Maddison, Mark, Tarpey, Patrick S., Davies, Helen R., Papaemmanuil, Elli, Stephens, Philip J., McLaren, Stuart, Butler, Adam P., Teague, Jon W., Jönsson, Göran, Garber, Judy E., Silver, Daniel, Miron, Penelope, Fatima, Aquila, Boyault, Sandrine, Langerød, Anita, Tutt, Andrew, Martens, John W.M., Aparicio, Samuel A.J.R., Borg, Åke, Salomon, Anne Vincent, Thomas, Gilles, Børresen-Dale, Anne-Lise, Richardson, Andrea L., Neuberger, Michael S., Futreal, P. Andrew, Campbell, Peter J., Stratton, Michael R.
Published 2012

Somatic mutations of the histone H3K27 demethylase, UTX, in human cancer

by van Haaften, Gijs, Dalgliesh, Gillian L, Davies, Helen, Chen, Lina, Bignell, Graham, Greenman, Chris, Edkins, Sarah, Hardy, Claire, O’Meara, Sarah, Teague, Jon, Butler, Adam, Hinton, Jonathan, Latimer, Calli, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J, Cole, Jennifer, Dunmore, Rebecca, Forbes, Simon, Jia, Mingming, Jones, David, Kok, Chai Yin, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maquire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Lee, Mulderrig, Mudie, Laura, Pleasance, Erin, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turner, Rachel, Turrell, Kelly, Varian, Jennifer, West, Sofie, Widaa, Sara, Wray, Paul, Collins, V Peter, Ichimura, Koichi, Law, Simon, Wong, John, Yuen, Siu Tsan, Leung, Suet Yi, Tonon, Giovanni, DePinho, Ronald A, Tai, Yu-Tzu, Anderson, Kenneth C, Kahnoski, Richard J., Massie, Aaron, Khoo, Sok Kean, Teh, Bin Tean, Stratton, Michael R, Futreal, P Andrew
Published 2009

The landscape of cancer genes and mutational processes in breast cancer

by Stephens, Philip J., Tarpey, Patrick S., Davies, Helen, Loo, Peter Van, Greenman, Chris, Wedge, David C., Nik-Zainal, Serena, Martin, Sancha, Varela, Ignacio, Bignell, Graham R., Yates, Lucy R., Papaemmanuil, Elli, Beare, David, Butler, Adam, Cheverton, Angela, Gamble, John, Hinton, Jonathan, Jia, Mingming, Jayakumar, Alagu, Jones, David, Latimer, Calli, Lau, King Wai, McLaren, Stuart, McBride, David J., Menzies, Andrew, Mudie, Laura, Raine, Keiran, Rad, Roland, Chapman, Michael Spencer, Teague, Jon, Easton, Douglas, Langerød, Anita, OSBREAC, Lee, Ming Ta Michael, Shen, Chen-Yang, Tee, Benita Tan Kiat, Huimin, Bernice Wong, Broeks, Annegien, Vargas, Ana Cristina, Turashvili, Gulisa, Martens, John, Fatima, Aquila, Miron, Penelope, Chin, Suet-Feung, Thomas, Gilles, Boyault, Sandrine, Mariani, Odette, Lakhani, Sunil R., van de Vijver, Marc, van ’t Veer, Laura, Foekens, John, Desmedt, Christine, Sotiriou, Christos, Tutt, Andrew, Caldas, Carlos, Reis-Filho, Jorge S., Aparicio, Samuel A. J. R., Salomon, Anne Vincent, Børresen-Dale, Anne-Lise, Richardson, Andrea L., Campbell, Peter J., Futreal, P. Andrew, Stratton, Michael R.
Published 2012