ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data

por Raine, Keiran M., Van Loo, Peter, Wedge, David C., Jones, David, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Tarpey, Patrick, Nik-Zainal, Serena, Campbell, Peter J.
Publicado en Curr Protoc Bioinformatics (2016)

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

por Forbes, Simon A., Tang, Gurpreet, Bindal, Nidhi, Bamford, Sally, Dawson, Elisabeth, Cole, Charlotte, Kok, Chai Yin, Jia, Mingming, Ewing, Rebecca, Menzies, Andrew, Teague, Jon W., Stratton, Michael R., Futreal, P. Andrew
Publicado 2010

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

por Forbes, Simon A., Bindal, Nidhi, Bamford, Sally, Cole, Charlotte, Kok, Chai Yin, Beare, David, Jia, Mingming, Shepherd, Rebecca, Leung, Kenric, Menzies, Andrew, Teague, Jon W., Campbell, Peter J., Stratton, Michael R., Futreal, P. Andrew
Publicado 2011

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

por Shepherd, Rebecca, Forbes, Simon A., Beare, David, Bamford, S., Cole, Charlotte G., Ward, Sari, Bindal, Nidhi, Gunasekaran, Prasad, Jia, Mingming, Kok, Chai Yin, Leung, Kenric, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Campbell, Peter J., Stratton, Michael R., Futreal, P. Andrew
Publicado 2011

High burden and pervasive positive selection of somatic mutations in normal human skin

por Martincorena, Iñigo, Roshan, Amit, Gerstung, Moritz, Ellis, Peter, Van Loo, Peter, McLaren, Stuart, Wedge, David C., Fullam, Anthony, Alexandrov, Ludmil B., Tubio, Jose M., Stebbings, Lucy, Menzies, Andrew, Widaa, Sara, Stratton, Michael R., Jones, Philip H., Campbell, Peter J.
Publicado en Science (2015)

Polygenic in vivo validation of cancer mutations using transposons

por Chew, Su Kit, Lu, Dong, Campos, Lia S, Scott, Kenneth L, Saci, Abdel, Wang, Juexuan, Collinson, Adam, Raine, Keiran, Hinton, Jonathan, Teague, Jon W, Jones, David, Menzies, Andrew, Butler, Adam P, Gamble, John, O’Meara, Sarah, McLaren, Stuart, Chin, Lynda, Liu, Pentao, Futreal, P Andrew
Publicado 2014

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

por Bignell, Graham R., Santarius, Thomas, Pole, Jessica C.M., Butler, Adam P., Perry, Janet, Pleasance, Erin, Greenman, Chris, Menzies, Andrew, Taylor, Sheila, Edkins, Sarah, Campbell, Peter, Quail, Michael, Plumb, Bob, Matthews, Lucy, McLay, Kirsten, Edwards, Paul A.W., Rogers, Jane, Wooster, Richard, Futreal, P. Andrew, Stratton, Michael R.
Publicado 2007

Tobacco exposure and somatic mutations in normal human bronchial epithelium

por Yoshida, Kenichi, Gowers, Kate HC, Lee-Six, Henry, Chandrasekharan, Deepak P, Coorens, Tim, Maughan, Elizabeth F, Beal, Kathryn, Menzies, Andrew, Millar, Fraser R, Anderson, Elizabeth, Clarke, Sarah E, Pennycuick, Adam, Thakrar, Ricky M, Butler, Colin R, Kakiuchi, Nobuyuki, Hirano, Tomonori, Hynds, Robert E, Stratton, Michael R, Martincorena, Inigo, Janes, Sam M, Campbell, Peter J
Publicado en Nature (2020)

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

por Campbell, Peter J, Stephens, Philip J, Pleasance, Erin D, O’Meara, Sarah, Li, Heng, Santarius, Thomas, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Hardy, Claire, Teague, Jon W, Menzies, Andrew, Goodhead, Ian, Turner, Daniel J, Clee, Christopher M, Quail, Michael A, Cox, Antony, Brown, Clive, Durbin, Richard, Hurles, Matthew E, Edwards, Paul A W, Bignell, Graham R, Stratton, Michael R, Futreal, P Andrew
Publicado 2008

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

por Campbell, Peter J, Yachida, Shinichi, Mudie, Laura J, Stephens, Philip J, Pleasance, Erin D, Stebbings, Lucy A, Morsberger, Laura A, Latimer, Calli, McLaren, Stuart, Lin, Meng-Lay, McBride, David J, Varela, Ignacio, Nik-Zainal, Serena A, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P, Teague, Jon W, Griffin, Constance A, Burton, John, Swerdlow, Harold, Quail, Michael A, Stratton, Michael R, Iacobuzio-Donahue, Christine, Futreal, P Andrew
Publicado 2010

Frequent mutation of the major cartilage collagen gene, COL2A1, in chondrosarcoma

por Tarpey, Patrick S, Behjati, Sam, Cooke, Susanna, Van Loo, Peter, Wedge, David C, Pillay, Nischalan, Marshall, John, O’Meara, Sarah, Davies, Helen, Nik-Zainal, Serena, Beare, David, Butler, Adam, Gamble, John, Hardy, Claire, Hinton, Jonathon, Jia, Ming Ming, Jayakumar, Alagu, Jones, David, Latimer, Calli, Maddison, Mark, Martin, Sancha, McLaren, Stuart, Menzies, Andrew, Mudie, Laura, Raine, Keiran, Teague, Jon W., Tubio, Jose, Halai, Dina, Tirabosco, Roberto, Amary, Fernanda, Campbell, Peter J, Stratton, Michael R, Flanagan, Adrienne M, Futreal, P. Andrew
Publicado 2013

Mutations in ZDHHC9, Which Encodes a Palmitoyltransferase of NRAS and HRAS, Cause X-Linked Mental Retardation Associated with a Marfanoid Habitus

por Raymond, F. Lucy, Tarpey, Patrick S., Edkins, Sarah, Tofts, Calli, O’Meara, Sarah, Teague, Jon, Butler, Adam, Stevens, Claire, Barthorpe, Syd, Buck, Gemma, Cole, Jennifer, Dicks, Ed, Gray, Kristian, Halliday, Kelly, Hills, Katy, Hinton, Jonathon, Jones, David, Menzies, Andrew, Perry, Janet, Raine, Keiran, Shepherd, Rebecca, Small, Alexandra, Varian, Jennifer, Widaa, Sara, Mallya, Uma, Moon, Jenny, Luo, Ying, Shaw, Marie, Boyle, Jackie, Kerr, Bronwyn, Turner, Gillian, Quarrell, Oliver, Cole, Trevor, Easton, Douglas F., Wooster, Richard, Bobrow, Martin, Schwartz, Charles E., Gecz, Jozef, Stratton, Michael R., Futreal, P. Andrew
Publicado 2007

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

por Stephens, Philip J., Greenman, Chris D., Fu, Beiyuan, Yang, Fengtang, Bignell, Graham R., Mudie, Laura J., Pleasance, Erin D., Lau, King Wai, Beare, David, Stebbings, Lucy A., McLaren, Stuart, Lin, Meng-Lay, McBride, David J., Varela, Ignacio, Nik-Zainal, Serena, Leroy, Catherine, Jia, Mingming, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Quail, Michael A., Burton, John, Swerdlow, Harold, Carter, Nigel P., Morsberger, Laura A., Iacobuzio-Donahue, Christine, Follows, George A., Green, Anthony R., Flanagan, Adrienne M., Stratton, Michael R., Futreal, P. Andrew, Campbell, Peter J.
Publicado 2011

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

por Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton, Jonathan, Gundem, Gunes, van Delft, Frederik W, Nik-Zainal, Serena, Jones, David R, Ramakrishna, Manasa, Titley, Ian, Stebbings, Lucy, Leroy, Catherine, Menzies, Andrew, Gamble, John, Robinson, Ben, Mudie, Laura, Raine, Keiran, O’Meara, Sarah, Teague, Jon W, Butler, Adam P, Cazzaniga, Giovanni, Biondi, Andrea, Zuna, Jan, Kempski, Helena, Muschen, Markus, Ford, Anthony M, Stratton, Michael R, Greaves, Mel, Campbell, Peter J
Publicado 2014

Whole exome sequencing of adenoid cystic carcinoma

por Stephens, Philip J., Davies, Helen R., Mitani, Yoshitsugu, Van Loo, Peter, Shlien, Adam, Tarpey, Patrick S., Papaemmanuil, Elli, Cheverton, Angela, Bignell, Graham R., Butler, Adam P., Gamble, John, Gamble, Stephen, Hardy, Claire, Hinton, Jonathan, Jia, Mingming, Jayakumar, Alagu, Jones, David, Latimer, Calli, McLaren, Stuart, McBride, David J., Menzies, Andrew, Mudie, Laura, Maddison, Mark, Raine, Keiran, Nik-Zainal, Serena, O’Meara, Sarah, Teague, Jon W., Varela, Ignacio, Wedge, David C., Whitmore, Ian, Lippman, Scott M., McDermott, Ultan, Stratton, Michael R., Campbell, Peter J., El-Naggar, Adel K., Futreal, P. Andrew
Publicado 2013

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

por Yates, Lucy R, Gerstung, Moritz, Knappskog, Stian, Desmedt, Christine, Gundem, Gunes, Loo, Peter Van, Aas, Turid, Alexandrov, Ludmil B, Larsimont, Denis, Davies, Helen, Li, Yilong, Ju, Young Seok, Ramakrishna, Manasa, Haugland, Hans Kristian, Lilleng, Peer Kaare, Nik-Zainal, Serena, McLaren, Stuart, Butler, Adam, Martin, Sancha, Glodzik, Dominic, Menzies, Andrew, Raine, Keiran, Hinton, Jonathan, Jones, David, Mudie, Laura J, Jiang, Bing, Vincent, Delphine, Greene-Colozzi, April, Adnet, Pierre-Yves, Fatima, Aquila, Maetens, Marion, Ignatiadis, Michail, Stratton, Michael R, Sotiriou, Christos, Richardson, Andrea L, Lønning, Per Eystein, Wedge, David C, Campbell, Peter J
Publicado en Nat Med (2015)

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

por Petljak, Mia, Alexandrov, Ludmil B., Brammeld, Jonathan S., Price, Stacey, Wedge, David C., Grossmann, Sebastian, Dawson, Kevin J., Ju, Young Seok, Iorio, Francesco, Tubio, Jose M.C., Koh, Ching Chiek, Georgakopoulos-Soares, Ilias, Rodríguez–Martín, Bernardo, Otlu, Burçak, O’Meara, Sarah, Butler, Adam P., Menzies, Andrew, Bhosle, Shriram G., Raine, Keiran, Jones, David R., Teague, Jon W., Beal, Kathryn, Latimer, Calli, O’Neill, Laura, Zamora, Jorge, Anderson, Elizabeth, Patel, Nikita, Maddison, Mark, Ng, Bee Ling, Graham, Jennifer, Garnett, Mathew J., McDermott, Ultan, Nik-Zainal, Serena, Campbell, Peter J., Stratton, Michael R.
Publicado en Cell (2019)

Mutations in the BRWD3 Gene Cause X-Linked Mental Retardation Associated with Macrocephaly

por Field, Michael , Tarpey, Patrick S. , Smith, Raffaella , Edkins, Sarah , O’Meara, Sarah , Stevens, Claire , Tofts, Calli , Teague, Jon , Butler, Adam , Dicks, Ed , Barthorpe, Syd , Buck, Gemma , Cole, Jennifer , Gray, Kristian , Halliday, Kelly , Hills, Katy , Jenkinson, Andrew , Jones, David , Menzies, Andrew , Mironenko, Tatiana , Perry, Janet , Raine, Keiran , Richardson, David , Shepherd, Rebecca , Small, Alexandra , Varian, Jennifer , West, Sofie , Widaa, Sara , Mallya, Uma , Wooster, Richard , Moon, Jenny , Luo, Ying , Hughes, Helen , Shaw, Marie , Friend, Kathryn L. , Corbett, Mark , Turner, Gillian , Partington, Michael , Mulley, John , Bobrow, Martin , Schwartz, Charles , Stevenson, Roger , Gecz, Jozef , Stratton, Michael R. , Andrew Futreal, P. , Lucy Raymond, F. 
Publicado 2007

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

por Ikediobi, Ogechi N., Davies, Helen, Bignell, Graham, Edkins, Sarah, Stevens, Claire, O’Meara, Sarah, Santarius, Thomas, Avis, Tim, Barthorpe, Syd, Brackenbury, Lisa, Buck, Gemma, Butler, Adam, Clements, Jody, Cole, Jennifer, Dicks, Ed, Forbes, Simon, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathan, Hunter, Chris, Jenkinson, Andy, Jones, David, Kosmidou, Vivienne, Lugg, Richard, Menzies, Andrew, Mironenko, Tatiana, Parker, Adrian, Perry, Janet, Raine, Keiran, Richardson, David, Shepherd, Rebecca, Small, Alex, Smith, Raffaella, Solomon, Helen, Stephens, Philip, Teague, Jon, Tofts, Calli, Varian, Jennifer, Webb, Tony, West, Sofie, Widaa, Sara, Yates, Andy, Reinhold, William, Weinstein, John N., Stratton, Michael R., Futreal, P. Andrew, Wooster, Richard
Publicado 2006

Mutations in the Gene Encoding the Sigma 2 Subunit of the Adaptor Protein 1 Complex, AP1S2, Cause X-Linked Mental Retardation

por Tarpey, Patrick S. , Stevens, Claire , Teague, Jon , Edkins, Sarah , O’Meara, Sarah , Avis, Tim , Barthorpe, Syd , Buck, Gemma , Butler, Adam , Cole, Jennifer , Dicks, Ed , Gray, Kristian , Halliday, Kelly , Harrison, Rachel , Hills, Katy , Hinton, Jonathon , Jones, David , Menzies, Andrew , Mironenko, Tatiana , Perry, Janet , Raine, Keiran , Richardson, David , Shepherd, Rebecca , Small, Alexandra , Tofts, Calli , Varian, Jennifer , West, Sofie , Widaa, Sara , Yates, Andy , Catford, Rachael , Butler, Julia , Mallya, Uma , Moon, Jenny , Luo, Ying , Dorkins, Huw , Thompson, Deborah , Easton, Douglas F. , Wooster, Richard , Bobrow, Martin , Carpenter, Nancy , Simensen, Richard J. , Schwartz, Charles E. , Stevenson, Roger E. , Turner, Gillian , Partington, Michael , Gecz, Jozef , Stratton, Michael R. , Futreal, P. Andrew , Raymond, F. Lucy 
Publicado 2006