Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

Human cancers often carry many somatically acquired genomic rearrangements, some of which may be implicated in cancer development. However, conventional strategies for characterizing rearrangements are laborious and low-throughput and have low sensitivity or poor resolution. We used massively parall...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Campbell, Peter J, Stephens, Philip J, Pleasance, Erin D, O’Meara, Sarah, Li, Heng, Santarius, Thomas, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Hardy, Claire, Teague, Jon W, Menzies, Andrew, Goodhead, Ian, Turner, Daniel J, Clee, Christopher M, Quail, Michael A, Cox, Antony, Brown, Clive, Durbin, Richard, Hurles, Matthew E, Edwards, Paul A W, Bignell, Graham R, Stratton, Michael R, Futreal, P Andrew
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705838/
https://ncbi.nlm.nih.gov/pubmed/18438408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.128
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