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PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data

High-throughput oligonucleotide microarrays are commonly employed to investigate genetic disease, including cancer. The algorithms employed to extract genotypes and copy number variation function optimally for diploid genomes usually associated with inherited disease. However, cancer genomes are ane...

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Autors principals: Greenman, Chris D., Bignell, Graham, Butler, Adam, Edkins, Sarah, Hinton, Jon, Beare, Dave, Swamy, Sajani, Santarius, Thomas, Chen, Lina, Widaa, Sara, Futreal, P. Andy, Stratton, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800165/
https://ncbi.nlm.nih.gov/pubmed/19837654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxp045
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